Jaguars vs. Colts Week 8: Trevor Lawrence, Bhayshul Tuten and a 92-Yard Pick-Six Bury Indy 42-7

Trevor Lawrence threw 14 passes on Sunday. Three of them went for touchdowns, and Lawrence was watching from the sideline before the fourth quarter was a few minutes old. That is about as much work as Indianapolis asked of Jacksonville's quarterback, and about as much resistance as the Colts offered all afternoon.

The Jacksonville Jaguars flattened the Indianapolis Colts 42-7 at EverBank Stadium, building a 28-0 halftime lead behind Lawrence's efficiency, two touchdowns from Bhayshul Tuten and a 92-yard interception return by safety Rayuan Lane III. Jacksonville has now won 12 straight home meetings with Indianapolis, a run that includes a 2016 game in London, and the Colts have not won in Jacksonville since 2014. Call it a streak, a hex or a zoning issue. It is not going anywhere.

The Jaguars, fresh off their bye, move to 5-2 and lead the AFC South by three games over Houston. The Colts fall to 2-6, have lost four straight and have dropped 13 of their last 15 games dating to last season, per the AP.

Ninety-Eight Yards, Then the Floodgates

Jacksonville's first touchdown drive set the tone for everything that followed. Pinned at its own 2, the offense needed 12 plays to cover 98 yards, with the big swing a 46-yard Lawrence strike to tight end Brenton Strange that reached the Indianapolis 32. Brian Thomas Jr. finished it with a 12-yard touchdown catch with 5:30 left in the first quarter.

Then the Colts started handing the ball over. Jonathan Taylor fumbled on what the AP described as a botched trick play, and rookie defensive end Bryan Thomas Jr., not to be confused with the receiver who scored the opener, recovered at midfield. Four plays later, Lawrence hit Nate Boerkircher for a 31-yard touchdown and a 14-0 lead with 7:14 left in the half.

Tuten made it 21-0 with 1:50 left before halftime, breaking three tackles on a 39-yard run that capped a seven-play, 80-yard drive. EverBank was loud. It was about to get louder.

The Turning Point: A 14-Point Swing in 10 Seconds

Indianapolis still had one real chance to make this a game. Trailing 21-0, the Colts drove all the way to the Jacksonville 8 in the final minute of the half, and a touchdown would have sent them to the locker room down two scores.

Instead, Daniel Jones threw for tight end Tyler Warren, the ball went through Warren's hands, and Lane snatched it and raced 92 yards the other way with 10 seconds left. Jones chased the return the length of the field and never caught up. What could have been 21-7 became 28-0, the third-largest halftime lead in franchise history, per the AP.

"Not a good throw," Jones said afterward, per Colts.com. Liam Coen described the Jaguars' mindset with a little more color. "The guys came in with a little blood in the water and we wanted to be able to jump on these guys at home," Coen said, per Jaguars.com.

Lawrence, Tuten and a Defense That Smelled It

Lawrence finished 10 of 14 for 210 yards and three touchdowns without an interception, averaging 9.2 yards per pass play, per Athlon Sports, before Quinn Ewers took over early in the fourth quarter. The only smudge on the day was three sacks for 35 yards.

Tuten was the engine. The back finished with 104 rushing yards on 16 carries and added a 25-yard touchdown on a screen from Lawrence on the final play of the third quarter. Chris Rodriguez Jr. chipped in a 28-yard touchdown run early in the third, and Jacksonville ran for 183 yards on 33 carries, a season best. Coen called it the team's best running performance of the season.

The defense did the rest. Jacksonville sacked Jones four times, with Travon Walker, Jalen Huskey and Foye Oluokun getting one apiece and Josh Hines-Allen and Arik Armstead splitting another. Linebacker Branson Combs, a regular on special teams, added a second-half interception, the first of Combs' career.

For Indianapolis, Jones went 19 of 28 for 144 yards with a touchdown and two interceptions. The lone Colts score was a 6-yard pass to Josh Downs with 3:59 left in the third quarter, long after the outcome was settled. Taylor, who entered the day leading the league in rushing touchdowns, managed 23 yards on eight carries, 19 of them on a single run, per Colts Wire, as the deficit took the run game off the table. Anthony Richardson Sr. replaced Jones early in the fourth quarter, Richardson's first regular-season action in more than a year.

The Numbers Behind It

• 12 straight home wins for Jacksonville over Indianapolis.
• 7 straight regular-season home wins for the Jaguars, every one by at least 17 points and by a combined 271-75, per the AP.
• 366 to 243 in total yards, with Jacksonville averaging 6.9 yards per play.
• 3 of 11 on third down for the Colts, who also went 0 for 2 on fourth down.
• 15 turnovers for Indianapolis through eight games, nine of them interceptions, per Colts.com.
• 183 rushing yards for Jacksonville against a Colts front playing its first game since trading DeForest Buckner.

What It Means

For Jacksonville, this was exactly the response a contender wants after a bye that followed the 34-31 heartbreaker against Houston in London. The Jaguars have a three-game cushion in the division, and they visit the Baltimore Ravens on a short week for a Thursday night game on Nov. 5.

The win did come with a bill. Defensive tackle DaVon Hamilton was carted off with a knee injury and ruled out, and safety Eric Murray (elbow), Walker (ribs), guard Ezra Cleveland (ankle) and Combs (arm) were also hurt, per the AP and Jaguars.com. Updates are expected Monday. "There's not many better humans, better competitors, team guys," Coen said of Hamilton.

For Indianapolis, the questions are only getting louder. The Colts traded Buckner and guard Quenton Nelson last week, the AP noted reports that the team is willing to move Taylor, and the trade deadline arrives Nov. 10. Shane Steichen would not commit to Jones as the starter. "I'm going to evaluate everything, every position going forward," Steichen said, per Colts.com. Steichen also put effort on the table. "The effort and the energy has to be there every week," Steichen said. "We're going to find out who loves ball." The Colts host the Dallas Cowboys on Nov. 8.

The Hex Lives On

Our preview of this game called it Jaguars 27, Colts 16, figuring Taylor would at least make Jacksonville's league-best run defense work for it. The Jaguars were not interested in making it close. The Colts have now gone 12 years without a win in this building, a drought that has outlasted head coaches, general managers, quarterbacks and a detour to London. Sunday's chapter was the shortest one yet: no suspense, no comeback, just a long ride home.

Stats via ESPN, Jaguars.com, Colts.com, Athlon Sports and Colts Wire. Postgame quotes as reported by Colts.com and Jaguars.com.